| Date | Location | Result | |
| 11/11/21 | Grand Rapids, Mich. | Otterbein 3, Westminster 0 (25-20,25-11,25-23) | Box score |
| 11/06/21 | New Wilmington, Pa. | Westminster 3, Bethany 0 (25-13,29-27,25-14) | Box score |
| 11/04/21 | New Wilmington, Pa. | Westminster 3, Grove City 1 (25-17,25-18,21-25,26-24) | Box score |
| 11/04/21 | Bethany, W.Va. | Bethany 3, Chatham 0 (27-25,25-19,25-21) | Box score |
| 11/02/21 | Greenville, Pa. | Grove City 3, Thiel 2 (25-19,22-25,14-25,25-17,15-11) | Box score |
| 11/02/21 | Pittsburgh, Pa. | Chatham 3, Geneva 1 (25-22,20-25,25-14,25-16) | Box score |
| 10/30/21 | New Wilmington, Pa. | Westminster 3, Chatham 0 (25-14,25-15,25-10) | Box score |
| 10/30/21 | Beaver Falls, Pa. | Geneva 3, Grove City 0 (25-15,25-17,25-15) | Box score |
| 10/30/21 | Washington, Pa. | Saint Vincent 3, W&J 2 (25-27,20-25,25-18,25-14,15-9) | Box score |
| 10/30/21 | Bethany, W.Va. | Bethany 3, Franciscan 0 (25-18,25-21,25-17) | Box score |
| 10/28/21 | Grove City, Pa. | Grove City 3, W&J 1 (22-25,25-13,25-19,25-21) | Box score |
| 10/28/21 | Steubenville, Ohio | Geneva 3, Franciscan 1 (21-25,25-12,25-19,30-28) | Box score |
| 10/28/21 | Waynesburg, Pa. | Westminster 3, Waynesburg 0 (25-16,25-8,25-22) | Box score |
| 10/28/21 | Latrobe, Pa. | Bethany 3, Saint Vincent 0 (25-19,25-20,25-19) | Box score |
| 10/28/21 | Pittsburgh, Pa. | Chatham 3, Thiel 0 (25-19,25-19,25-21) | Box score |
| 10/26/21 | Beaver Falls, Pa. | Bethany 3, Geneva 0 (25-20,25-15,29-27) | Box score |
| 10/26/21 | Washington, Pa. | Thiel 3, W&J 1 (25-19,23-25,25-13,25-20) | Box score |
| 10/26/21 | Pittsburgh, Pa. | Chatham 3, Saint Vincent 0 (26-24,25-20,25-16) | Box score |
| 10/26/21 | Beaver Falls, Pa. | Bethany 3, Geneva 2 (16-25,20-25,25-16,28-26,15-9) | Box score |
| 10/26/21 | Grove City, Pa. | Westminster 3, Grove City 0 (26-24,25-18,25-13) | Box score |
| 10/23/21 | Greenville, Pa. | Capital 3, Thiel 2 (11-25,27-25,25-20,18-25,15-9) | Box score |
| 10/23/21 | Bethany, W.Va. | Bethany 3, Grove City 1 (25-27,25-21,25-13,25-19) | Box score |
| 10/23/21 | New Wilmington, Pa. | Westminster 3, Franciscan 0 (25-17,25-9,25-23) | Box score |
| 10/23/21 | Greenville, Pa. | Capital 3, Saint Vincent 0 (25-13,25-15,25-11) | Box score |
| 10/23/21 | Greenville, Pa. | Thiel 3, Saint Vincent 2 (25-17,25-16,19-25,16-25,15-10) | Box score |
| 10/23/21 | Beaver Falls, Pa. | Geneva 3, W&J 0 (25-22,25-19,25-17) | Box score |
| 10/23/21 | Waynesburg, Pa. | Chatham 3, Waynesburg 1 (25-20,25-22,17-25,25-23) | Box score |
| 10/21/21 | Washington, Pa. | W&J 3, Bethany 2 (33-35,21-25,25-23,29-27,15-13) | Box score |
| 10/21/21 | Grove City, Pa. | Thiel 3, Grove City 0 (25-22,25-23,25-21) | Box score |
| 10/21/21 | Steubenville, Ohio | Chatham 3, Franciscan 2 (22-25,25-11,25-27,26-24,15-11) | Box score |
| 10/21/21 | Latrobe, Pa. | Saint Vincent 3, Waynesburg 1 (25-16,25-18,22-25,25-10) | Box score |
| 10/21/21 | Beaver Falls, Pa. | Westminster 3, Geneva 0 (25-22,25-16,25-21) | Box score |
| 10/19/21 | Greenville, Pa. | Thiel 3, Waynesburg 0 (25-17,25-21,25-18) | Box score |
| 10/19/21 | Latrobe, Pa. | Grove City 3, Saint Vincent 0 (25-19,26-24,30-28) | Box score |
| 10/19/21 | New Wilmington, Pa. | Westminster 3, Bethany 1 (25-19,25-18,23-25,25-23) | Box score |
| 10/19/21 | Pittsburgh, Pa. | Chatham 3, Geneva 1 (25-16,21-25,25-15,25-20) | Box score |
| 10/18/21 | Washington, Pa. | Geneva 3, W&J 1 (25-22,18-25,25-22,25-22) | Box score |
| 10/18/21 | Steubenville, Ohio | Bethany 3, Franciscan 0 (25-19,25-17,25-22) | Box score |
| 10/16/21 | Beaver Falls, Pa. | Geneva 3, Saint Vincent 1 (22-25,25-14,29-27,25-20) | Box score |
| 10/16/21 | Bethany, W.Va. | Bethany 3, Waynesburg 0 (25-19,25-20,25-20) | Box score |
| 10/16/21 | Steubenville, Ohio | Franciscan 3, W&J 1 (25-17,25-23,21-25,25-22) | Box score |
| 10/16/21 | New Wilmington, Pa. | Westminster 3, Thiel 0 (25-22,25-19,25-11) | Box score |
| 10/16/21 | Grove City, Pa. | Grove City 3, Chatham 1 (22-25,25-23,25-17,25-18) | Box score |
| 10/14/21 | Greenville, Pa. | Thiel 3, Geneva 0 (25-18,25-19,25-23) | Box score |
| 10/14/21 | Grove City, Pa. | Grove City 3, Waynesburg 1 (25-13,20-25,25-16,25-20) | Box score |
| 10/14/21 | Pittsburgh, Pa. | Bethany 3, Chatham 0 (25-17,27-25,25-22) | Box score |
| 10/14/21 | Latrobe, Pa. | Saint Vincent 3, Franciscan 0 (25-22,25-23,25-10) | Box score |
| 10/14/21 | Washington, Pa. | Westminster 3, W&J 0 (25-10,25-11,25-13) | Box score |
| 10/12/21 | Waynesburg, Pa. | Geneva 3, Waynesburg 2 (23-25,25-14,25-15,22-25,15-11) | Box score |
| 10/12/21 | Bethany, W.Va. | Bethany 3, Thiel 0 (25-20,25-20,25-21) | Box score |
| 10/12/21 | New Wilmington, Pa. | Westminster 3, Saint Vincent 0 (25-21,25-10,25-19) | Box score |
| 10/12/21 | Washington, Pa. | Chatham 3, W&J 1 (25-22,25-23,18-25,25-12) | Box score |
| 10/12/21 | Steubenville, Ohio | Grove City 3, Franciscan 0 (25-13,25-14,25-17) | Box score |
| 10/09/21 | Greenville, Pa. | Thiel 3, W&J 0 (25-16,25-18,25-16) | Box score |
| 10/09/21 | Oberlin, Ohio | Oberlin 3, Saint Vincent 1 (25-22,25-23,24-26,25-14) | Box score |
| 10/09/21 | Pittsburgh, Pa. | Chatham 3, Waynesburg 0 (25-15,25-10,25-14) | Box score |
| 10/09/21 | Greenville, Pa. | Grove City 3, W&J 1 (25-20,25-14,23-25,25-18) | Box score |
| 10/09/21 | Pittsburgh, Pa. | Westminster 3, Waynesburg 0 (25-13,25-21,25-13) | Box score |
| 10/09/21 | Greenville, Pa. | Thiel 3, Grove City 0 (28-26,25-19,25-18) | Box score |
| 10/09/21 | Pittsburgh, Pa. | Westminster 3, Chatham 1 (22-25,25-19,25-15,25-22) | Box score |
| 10/08/21 | Bethany, W.Va. | Allegheny 3, Bethany 1 (25-19,25-18,21-25,28-26) | Box score |
| 10/07/21 | Latrobe, Pa. | Penn St.-Altoona 3, Saint Vincent 2 (25-23,25-22,22-25,19-25,15-6) | Box score |
| 10/07/21 | Greenville, Pa. | Thiel 3, Franciscan 1 (22-25,25-18,25-17,26-24) | Box score |
| 10/06/21 | Pittsburgh, Pa. | Chatham 3, Grove City 2 (25-15,22-25,18-25,25-21,19-17) | Box score |
| 10/06/21 | Bethany, W.Va. | Westminster 3, Bethany 0 (25-20,25-20,25-13) | Box score |
| 10/05/21 | Hiram, Ohio | Hiram 3, Thiel 0 (25-16,25-15,25-17) | Box score |
| 10/05/21 | Steubenville, Ohio | Waynesburg 3, Franciscan 1 (25-22,25-18,21-25,25-16) | Box score |
| 10/02/21 | Waynesburg, Pa. | Saint Vincent 3, Waynesburg 1 (25-19,25-15,19-25,25-17) | Box score |
| 10/02/21 | Waynesburg, Pa. | Thiel 3, Saint Vincent 1 (16-25,25-16,25-17,25-22) | Box score |
| 10/02/21 | Waynesburg, Pa. | Thiel 3, Waynesburg 1 (24-26,25-16,25-18,25-19) | Box score |
| 10/02/21 | Lancaster, Pa. | Grove City 3, Lancaster Bible 1 (25-13,19-25,25-18,25-18) | Box score |
| 10/02/21 | Beaver Falls, Pa. | Geneva 3, Franciscan 1 (25-11,25-20,24-26,25-10) | Box score |
| 10/02/21 | Lancaster, Pa. | Grove City 3, Widener 0 (25-12,25-18,25-18) | Box score |
| 09/30/21 | Grove City, Pa. | Grove City 3, Franciscan 1 (26-24,27-25,27-29,25-20) | Box score |
| 09/30/21 | Greenville, Pa. | Bethany 3, Thiel 0 (25-23,25-13,25-20) | Box score |
| 09/30/21 | Latrobe, Pa. | Westminster 3, Saint Vincent 0 (25-21,25-20,25-18) | Box score |
| 09/30/21 | Pittsburgh, Pa. | Chatham 3, La Roche 0 (25-16,25-20,25-13) | Box score |
| 09/28/21 | Waynesburg, Pa. | Grove City 3, Waynesburg 1 (25-21,20-25,26-24,30-28) | Box score |
| 09/28/21 | Beaver Falls, Pa. | Geneva 3, Thiel 0 (25-11,25-17,25-21) | Box score |
| 09/28/21 | New Wilmington, Pa. | Westminster 3, W&J 0 (25-17,25-17,25-14) | Box score |
| 09/25/21 | Pittsburgh, Pa. | Susquehanna 3, Westminster 1 (25-19,25-17,15-25,25-15) | Box score |
| 09/25/21 | Washington, Pa. | Waynesburg 3, W&J 2 (25-19,25-15,22-24,22-25,15-6) | Box score |
| 09/25/21 | Latrobe, Pa. | Geneva 3, Saint Vincent 0 (25-19,25-17,25-20) | Box score |
| 09/25/21 | Franklin, Ind. | Bethany 3, Franklin 2 (27-25,16-25,25-19,21-25,15-11) | Box score |
| 09/25/21 | Latrobe, Pa. | Chatham 3, Geneva 1 (25-11,25-12,23-25,25-22) | Box score |
| 09/25/21 | Washington, Pa. | Franciscan 3, Waynesburg 2 (20-25,25-23,23-25,25-17,15-10) | Box score |
| 09/25/21 | Latrobe, Pa. | Chatham 3, Saint Vincent 0 (25-20,25-18,25-21) | Box score |
| 09/25/21 | Washington, Pa. | W&J 3, Franciscan 2 (21-25,25-18,13-25,25-23,15-11) | Box score |
| 09/25/21 | Franklin, Ind. | Anderson 3, Bethany 1 (25-17,18-25,25-22,25-18) | Box score |
| 09/25/21 | Pittsburgh, Pa. | Westminster 3, Carnegie Mellon 0 (37-35,25-19,25-16) | Box score |
| 09/24/21 | Grove City, Pa. | Grove City 3, Pitt.-Greensburg 0 (25-13,26-24,25-21) | Box score |
| 09/24/21 | Franklin, Ind. | Bethany 3, Trine 2 (25-23,22-25,25-14,17-25,15-11) | Box score |
| 09/24/21 | Pittsburgh, Pa. | Mount Union 3, Westminster 0 (27-25,25-19,25-17) | Box score |
| 09/23/21 | Latrobe, Pa. | W&J 3, Saint Vincent 1 (27-25,26-24,17-25,25-23) | Box score |
| 09/23/21 | Beaver Falls, Pa. | Geneva 3, Waynesburg 1 (25-21,25-18,20-25,25-21) | Box score |
| 09/23/21 | Pittsburgh, Pa. | Chatham 3, Franciscan 0 (25-13,25-18,25-21) | Box score |
| 09/22/21 | New Wilmington, Pa. | Westminster 3, Grove City 0 (25-22,25-12,25-16) | Box score |
| 09/22/21 | New Wilmington, Pa. | Grove City 3, Geneva 1 (22-25,25-21,25-15,25-19) | Box score |
| 09/22/21 | New Wilmington, Pa. | Westminster 3, Geneva 1 (25-9,21-25,25-14,25-21) | Box score |
| 09/21/21 | Greenville, Pa. | Chatham 3, Thiel 1 (26-24,19-25,26-24,25-16) | Box score |
| 09/21/21 | Steubenville, Ohio | Saint Vincent 3, Franciscan 0 (25-12,25-20,25-18) | Box score |
| 09/21/21 | Waynesburg, Pa. | Bethany 3, Waynesburg 0 (25-14,25-8,25-14) | Box score |
| 09/18/21 | Grove City, Pa. | Grove City 3, Saint Vincent 0 (25-15,27-25,25-17) | Box score |
| 09/18/21 | Grove City, Pa. | Saint Vincent 3, Bethany 1 (20-25,25-22,25-22,28-26) | Box score |
| 09/18/21 | Grove City, Pa. | Grove City 3, Bethany 2 (18-25,25-15,23-25,25-15,15-11) | Box score |
| 09/18/21 | Steubenville, Ohio | Thiel 3, Franciscan 1 (25-12,17-25,25-17,25-20) | Box score |
| 09/18/21 | Steubenville, Ohio | Westminster 3, Thiel 2 (25-18,29-31,25-11,24-26,15-11) | Box score |
| 09/18/21 | Wooster, Ohio | Bluffton 3, Geneva 0 (25-15,25-18,25-21) | Box score |
| 09/18/21 | Meadville, Pa. | Waynesburg 3, La Roche 1 (25-16,21-25,25-12,25-21) | Box score |
| 09/18/21 | Wooster, Ohio | Roanoke 3, Geneva 1 (25-8,25-16,19-25,25-22) | Box score |
| 09/18/21 | Meadville, Pa. | Chatham 3, Mount Aloysius 0 (25-13,27-25,25-21) | Box score |
| 09/18/21 | Steubenville, Ohio | Westminster 3, Franciscan 0 (25-14,25-16,25-7) | Box score |
| 09/17/21 | Meadville, Pa. | Waynesburg 3, Mount Aloysius 1 (27-25,26-24,24-26,25-21) | Box score |
| 09/17/21 | Meadville, Pa. | Allegheny 3, Chatham 0 (25-16,25-22,25-18) | Box score |
| 09/17/21 | Univ. Heights, Ohio | Geneva 3, John Carroll 1 (25-22,27-25,12-25,25-21) | Box score |
| 09/17/21 | Wooster, Ohio | Bluffton 3, W&J 1 (25-23,25-21,21-25,25-12) | Box score |
| 09/17/21 | Meadville, Pa. | Chatham 3, La Roche 1 (22-25,25-17,25-21,25-19) | Box score |
| 09/17/21 | Meadville, Pa. | Allegheny 3, Waynesburg 1 (25-16,21-25,25-19,25-21) | Box score |
| 09/17/21 | Wooster, Ohio | Wooster 3, W&J 1 (25-15,22-25,25-8,25-20) | Box score |
| 09/16/21 | Pittsburgh, Pa. | Franciscan 3, La Roche 2 (25-21,25-22,16-25,23-25,15-11) | Box score |
| 09/16/21 | Bethany, W.Va. | Bethany 3, Pitt.-Greensburg 0 (25-14,25-23,25-20) | Box score |
| 09/15/21 | Greensburg, Pa. | Pitt.-Greensburg 3, Saint Vincent 0 (25-20,25-18,25-19) | Box score |
| 09/15/21 | Erie, Pa. | Penn State Behrend 3, Grove City 1 (25-7,22-25,25-15,25-10) | Box score |
| 09/15/21 | Pittsburgh, Pa. | Penn St.-Altoona 3, Chatham 2 (20-25,24-26,25-20,25-19,15-7) | Box score |
| 09/15/21 | Waynesburg, Pa. | Waynesburg 3, W&J 0 (25-19,25-13,25-22) | Box score |
| 09/11/21 | Erie, Pa. | Westminster 3, Penn State Behrend 0 (27-25,25-15,25-22) | Box score |
| 09/11/21 | Cresson, Pa. | Saint Vincent 3, Mount Aloysius 0 (25-14,25-15,25-20) | Box score |
| 09/11/21 | Erie, Pa. | Baldwin Wallace 3, Westminster 2 (27-25,27-25,18-25,20-25,15-12) | Box score |
| 09/11/21 | McKeesport, Pa. | Waynesburg 3, Penn St.-Gr Alleghen 0 (25-17,25-21,25-21) | Box score |
| 09/11/21 | Brockport, N.Y. | Rochester 3, Thiel 1 (25-23,25-20,19-25,25-16) | Box score |
| 09/11/21 | Bethany, W.Va. | Bethany 3, Chatham 0 (25-12,25-14,25-15) | Box score |
| 09/11/21 | Grove City, Pa. | Grove City 3, La Roche 0 (25-16,25-16,25-21) | Box score |
| 09/11/21 | Bexley, Ohio | Geneva 3, Capital 1 (25-18,13-25,25-20,25-18) | Box score |
| 09/11/21 | Bethany, W.Va. | Chatham 3, W&J 1 (20-25,25-15,26-24,25-18) | Box score |
| 09/11/21 | Grove City, Pa. | Grove City 3, Regent 0 (25-14,25-15,25-15) | Box score |
| 09/11/21 | McKeesport, Pa. | Waynesburg 3, Pitt.-Greensburg 0 (25-16,25-16,27-25) | Box score |
| 09/11/21 | Delaware, Ohio | Mount Union 3, Geneva 0 (25-13,25-13,25-9) | Box score |
| 09/11/21 | Brockport, N.Y. | Nazareth 3, Thiel 2 (23-25,25-16,24-26,25-10,15-8) | Box score |
| 09/11/21 | Bethany, W.Va. | Bethany 3, W&J 0 (25-20,25-15,25-16) | Box score |
| 09/10/21 | Westerville, Ohio | Otterbein 3, Geneva 0 (25-15,25-23,25-17) | Box score |
| 09/10/21 | Brockport, N.Y. | SUNY Brockport 3, Thiel 1 (25-8,25-17,23-25,25-12) | Box score |
| 09/10/21 | Erie, Pa. | John Carroll 3, Westminster 1 (16-25,25-19,25-19,25-16) | Box score |
| 09/10/21 | Westerville, Ohio | Heidelberg 3, Geneva 1 (25-20,23-25,25-14,25-13) | Box score |
| 09/10/21 | Erie, Pa. | Westminster 3, Fredonia 1 (23-25,25-18,25-22,25-16) | Box score |
| 09/09/21 | Pittsburgh, Pa. | Chatham 3, Penn St.-Gr Alleghen 0 (25-14,25-20,25-15) | Box score |
| 09/07/21 | Berea, Ohio | Baldwin Wallace 3, Thiel 0 (25-11,25-21,25-11) | Box score |
| 09/07/21 | Pittsburgh, Pa. | Chatham 3, Pitt.-Greensburg 0 (25-21,25-11,25-9) | Box score |
| 09/04/21 | Latrobe, Pa. | Hiram 3, Waynesburg 0 (25-16,26-24,25-18) | Box score |
| 09/04/21 | Latrobe, Pa. | Westminster 3, Pitt.-Bradford 0 (25-21,25-6,25-15) | Box score |
| 09/04/21 | Marietta, Ohio | Capital 3, W&J 0 (25-20,25-20,25-17) | Box score |
| 09/04/21 | Cleveland, Ohio | Earlham 3, Bethany 0 (25-23,25-19,25-20) | Box score |
| 09/04/21 | Grand Rapids, Mich. | Grove City 3, Kalamazoo 0 (25-22,25-11,25-20) | Box score |
| 09/04/21 | Virginia Beach, Va. | Southern Va. 3, Geneva 0 (25-11,25-12,25-16) | Box score |
| 09/04/21 | Latrobe, Pa. | Hiram 3, Saint Vincent 0 (25-16,25-19,25-17) | Box score |
| 09/04/21 | Latrobe, Pa. | Westminster 3, Pitt.-Greensburg 0 (25-11,25-7,25-20) | Box score |
| 09/04/21 | Alliance, Ohio | SUNY Geneseo 3, Thiel 0 (25-13,25-14,25-21) | Box score |
| 09/04/21 | Grand Rapids, Mich. | Augsburg 3, Grove City 2 (25-20,21-25,18-25,25-12,15-9) | Box score |
| 09/04/21 | Marietta, Ohio | Franklin 3, W&J 1 (25-8,25-22,22-25,25-21) | Box score |
| 09/04/21 | Latrobe, Pa. | Pitt.-Bradford 3, Waynesburg 2 (25-23,18-25,18-25,25-16,15-11) | Box score |
| 09/04/21 | Virginia Beach, Va. | Va. Wesleyan 3, Geneva 0 (25-18,25-12,25-16) | Box score |
| 09/04/21 | Alliance, Ohio | Mount Union 3, Thiel 0 (25-12,25-16,25-14) | Box score |
| 09/04/21 | Cleveland, Ohio | Case Western Reserve 3, Bethany 0 (25-9,25-19,25-15) | Box score |
| 09/03/21 | Latrobe, Pa. | Westminster 3, Hiram 0 (25-19,25-21,25-15) | Box score |
| 09/03/21 | Virginia Beach, Va. | Geneva 3, Mount Aloysius 1 (21-25,25-21,25-14,25-15) | Box score |
| 09/03/21 | Latrobe, Pa. | Westminster 3, Allegheny 0 (25-14,25-17,25-13) | Box score |
| 09/03/21 | Cleveland, Ohio | John Carroll 3, Bethany 2 (24-26,20-25,25-22,25-19,15-12) | Box score |
| 09/03/21 | Alliance, Ohio | Wooster 3, Thiel 1 (25-15,17-25,29-27,25-20) | Box score |
| 09/03/21 | Marietta, Ohio | Marietta 3, W&J 1 (25-14,23-25,25-15,25-22) | Box score |
| 09/03/21 | Latrobe, Pa. | Waynesburg 3, Pitt.-Greensburg 0 (25-19,25-12,25-22) | Box score |
| 09/03/21 | Virginia Beach, Va. | Meredith 3, Geneva 0 (25-15,25-23,25-6) | Box score |
| 09/03/21 | Grand Rapids, Mich. | Otterbein 3, Grove City 0 (25-19,26-24,25-21) | Box score |
| 09/03/21 | Grand Rapids, Mich. | Calvin 3, Grove City 0 (25-14,25-15,25-19) | Box score |
| 09/03/21 | Latrobe, Pa. | Saint Vincent 3, Pitt.-Bradford 2 (25-12,25-21,25-27,19-25,15-12) | Box score |
| 09/03/21 | Alliance, Ohio | Carnegie Mellon 3, Thiel 1 (25-23,25-11,15-25,25-12) | Box score |
| 09/03/21 | Marietta, Ohio | Kenyon 3, W&J 2 (27-25,22-25,19-25,25-21,15-8) | Box score |
| 09/03/21 | Latrobe, Pa. | Allegheny 3, Waynesburg 0 (25-19,26-24,25-21) | Box score |
| 09/03/21 | Latrobe, Pa. | Saint Vincent 3, Pitt.-Greensburg 0 (25-12,25-15,25-16) | Box score |
| 09/01/21 | Waynesburg, Pa. | Waynesburg 3, La Roche 0 (25-22,25-12,25-23) | Box score |
| 09/01/21 | Greensburg, Pa. | Grove City 3, Pitt.-Greensburg 0 (25-23,25-10,25-21) | Box score |
| 09/01/21 | Meadville, Pa. | Westminster 3, Allegheny 1 (25-17,15-25,25-14,25-22) | Box score |
| 09/01/21 | Washington, Pa. | Hiram 3, W&J 0 (25-10,25-8,25-13) | Box score |
| 09/01/21 | Greenville, Pa. | Penn State Behrend 3, Thiel 0 (25-21,25-15,25-20) | Box score |
| 09/01/21 | Steubenville, Ohio | Baldwin Wallace 3, Franciscan 1 (16-25,25-14,25-15,25-22) | Box score |